Wednesday, March 22, 2006

Update on the Relationship between Sleep and Metabolism

The Relationship between Sleep and Metabolism

Karine Spiegel, PhD, and colleagues published an article in the December 7, 2004 issue of the Annuals of Internal Medicine that suggests that sleep restriction can lead to weight gain. They found that sleep restriction (4 hrs /night) leads to decreased levels of the hormone Leptin and increased levels of Ghrelin, another hormone. The alteration of the levels of these appetite and energy regulating hormones was associated with increased hunger and appetite in the study. This study adds to the evidence linking insufficient sleep to obesity.

More recently, Dr. Henry Klar Yaggi and colleagues reported on a 15-year study that examined the association between sleep duration and the risk of developing type 2 diabetes mellitus. The prospective observational Massachusetts Male Aging Study found that men reporting short sleep duration (6 or less hours per night) and men reporting long sleep duration (more than 8 hours per night) were at significantly increased risk for developing diabetes compared to those getting 7-8 hours of sleep.

Insufficient nocturnal sleep can be caused by either a sleep disorder or voluntary sleep deprivation. Excessive sleep is usually caused by an underlying sleep disorder. Abnormal nocturnal sleep durations have been linked with obesity, impaired glucose tolerance, and diabetes mellitus.

It is important for physicians to counsel their overweight and obese patients to allow for 8 hours of sleep per night. Since obstructive sleep apnea is both a cause and consequence of obesity, practitioners should screen their obese patients for this common disorder. Useful symptoms to ask about include snoring, prolonged sleep duration, frequent nocturnal awakenings, and excessive daytime sleepiness.


labaker12345 said...

Thought you all might like to know the WebMD sleep expert, Dr. Michael Breus, is going be hosting a live web chat on Saturday night (April 1) for two hours beginning at 11:30pm EST. He's going to answer sleep-related questions in a chat room on Apparently, this all part of Carpenter CO. National Sleep Better Night.

: Joseph j7uy5 said...

That is really interesting. It may give a little extra motivation to people who have trouble finding the motivation to adjust their sleep habits.

bcregan said...
This comment has been removed by a blog administrator.
bcregan said...

I am a registered Polysomnography tech working in upstate NY. I am also going to school full time. I have had an increase in my appetite, and gained weight since working at night and going to school. No matter how much I work out I seem to stay the same and this is not normal for me because I am into fitness, and used to run 15 miles a day while in the service, and now I feel drained. I know that once school is over I can change my sleep habits and increase my energy. It just goes to show how sleep affects numerous physical aspects of the human body. I am new to this (BLOGING) and really enjoyed your posting and look forward to more, thanks a lot!!

big_guy said...

I have a bone to pick with most of the health care professionals and the media and anyone else who passes on the latest info on a disease as fact. I have spent the whole day searching about apnea and If I had a dollar for every hit that came said "being overweight causes" ... Damn! I also have diabetes type I (that's one) and have only been overweight for the past 10 years of which 7 are after I was diagnosed with apnea. I have to fight with new doctors all the time. I say, "I have type I diabetes." And they say, "are you sure?" Yea after having diabetes for 25 years of my life, I am sure! Aaaarrrrg! What people don't know is that there is a high percentage of Japanese people with apnea. I am not talking about sumo wretslers. So come on you Pulmonologists, ENTs, GP's, MD's, RN's, RD's and any other of you SOB's expand your thinking and analysis or get OUT of the profession. There should be criminal charges brought againt those in the health care field! You are dealing with HUMAN LIVES here. Which came first the chicken or the egg? If you think you know the answer, you aren't a questioning individual. Think again. Remember, when I come in to your office, lab, hospital, teaching room, that I HIRED YOU! You will submit to my questions and my questioning of your reasoning. You work for me. Drop the attitude that I am lucky to be served by YOU!

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Diabetes Supply said...

At first, your blood sugar level may rise so slowly that you may not know that anything is wrong. One-third of all people who have diabetes do not know that they have the disease. If you do have Type 2 Diabetes Symptom, they may include: Feeling thirsty. Having to urinate more than usual, Feeling more hungry than usual, Losing weight without trying to.

Diabetes Supply said...

At first, your blood sugar level may rise so slowly that you may not know that anything is wrong. One-third of all people who have diabetes do not know that they have the disease. If you do have Type 2 Diabetes Symptom, they may include: Feeling thirsty. Having to urinate more than usual, Feeling more hungry than usual, Losing weight without trying to.

Orlena Oriel said...

There is a concept that people who sleep a lot run the risk of gaining weight. Well, this is not false, but then people who do not sleep well also run the risk of gaining weight! Appropriate amount of sleeping is very necessary to keep from getting obese. Even children, who do not sleep well, might run the risk of getting obese. However, in the modern times there are a plenty of ways that can help a person to lose weight, for example the weight loss pills.

Sharon said...


7.9% of the United States population is suffering from a form of Diabetes. That is over 23 million people! Now, more than ever, it is important for organizations such as yourself. We here, at (a site dedicated towards disease and their treatments), believe in the work you do and would like to coincide for the fight against diabetes. If you could, please list us as a resource or host our social book mark button, it would be much appreciated. Separately, we can make advancements, but together we can find a cure.
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Thank You,
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