Tuesday, December 06, 2005


A reader (Dozy) asks, Does Ambien affect sleep architecture? If so, how?
Ambien is a benzodiazepine agonist that binds to the alpha 1 subtype of the GABA-A receptor. It is therefore more selective then the benzodiazepines such as valium, ativan, and xanax.
The benzos (valium, etc) tend to increase stage 2 sleep while decreasing deep sleep (stage 3 and 4 ) and decreasing REM sleep. These effects are mild.
Ambien has minimal effects on sleep architecture. In many studies, its effect on sleep stages is no different than placebo. In at least one study, it increased deep (slow wave) sleep.
The brief answer to your question is that, in short-term studies, Ambien decreases sleep latency (time to fall asleep) and increases total sleep time with no significant effect on sleep architecture.


Tex said...

I'm looking for comments on ambien cr, which is time release and supposedly can be used for long terms.
Also, what is the effect of switching from one sleep medicine to another on a regular basis?

FDF said...

Do not take more of the medication than is prescribed for you. Valtrex is habit forming. You can become physically and psychologically dependent on the medication. Do not take more than the prescribed amount.

FDF said...

Zyrtec and may cause dizziness. If you experience drowsiness or dizziness, avoid these activities.(used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor

FDF said...

Naproxen is used to relieve anxiety, nervousness, and tension associated with anxiety disorders. Naproxen is also used to treat panic disorders.

FDF said...

What should I discuss with my healthcare provider before taking Lortab?

Anonymous said...

Some of the striking informative tidbits associated with the anti-anxiety medication valium make it apparent that valium is a prescription-based drug for treating anxiety, it belongs to the medicine group termed as benzodiazepines and is duly approved by the FDA (Food and Drugs Administration) for treating anxiety disorders.

Ramesh said...

Hell Have been using Stillnox (ambien) for only 2 months, and the withdrawal has been terrible. I started the Ambien to help sleep following surgery, and this is my first and only experience with any sleep medication. I first tried just stopping using Ambien completely, but the anxiety was terrible. I slowly weaned myself over several weeks, and am now sleeping without the Ambien. Have never had nightmares before in my life, but now I am having them many times every night.

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